Dose of Anti-acetylcholinesterase in MG treatment

from Continuum 2009  

Mestinon (pyridostigmine bromide)

Oral dose 30-50 mg q 4-6 hours
Intramuscular dose 2.0 mg q 4-6 hours
Intravenous dose 0.7 mg q 4-6 hours
pediatric oral dose 1.0 mg/kg to 7.0 mg/kg q 4-6 hours

Neostigmine (prostigmine)

oral dose 15 mg q 4-6 hours
intramuscular dose 1.5 mg (methylsulfate) q 4-6 hours
Intravenous dose 0.5 mg (methylsulfate) q 4-6 hours
pediatric 0.3 mg/kg in divided doses 2-3 times per day

Ambenonium chloride (mytelase)

for patients allergic to or developing a rash to bromides
oral dose 7.5 mg in divided doses 3-4 times daily
pediatric oral dose .15 mg/kg up to a maximum of 1.5 mg/kg/d in divided doses
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